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Avon Longitudinal Study of Parents and Children (ALSPAC)
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Sample details

ALSPAC, also known as Children of the 90s, is a prospective, population-based birth cohort study. The study was designed to understand the ways in which genetic and environmental factors interact to influence health, behaviour and development across the lifespan. Over 14,000 children born between April 1991 and December 1992 were initially included in the study from over 14,500 pregnant mothers recruited antenatally. ALSPAC participants were born to mothers residing in the Bristol & District Health Authority Area (Former Avon Health Authority Area) at the time of recruitment. Further recruitment occurred at age 7 years, with over 450 additional children recruited into the study. Similarly between age 8-18 years, over 250 further children were added to the cohort, and after turning 18, just under 200 further children enrolled in the study. Data has primarily been collected for the ALSPAC participants and mothers, but has also been collected regarding the mothers' partners, and the children's fathers and grandparents.

Study design
Cohort - birth, Cohort - primary caregiver and child, Cohort

Number of participants at first data collection

14,541 (mothers)

14,062 (children)

Age at first data collection

Birth (children)

Varied (mothers)

Participant year of birth

1991 - 1992 (children)

Varied (mothers)

Participant sex
All

Representative sample at baseline?
No

Sample features

Intergenerational
Pregnant people
Dataset details
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Countries

England, United Kingdom of Great Britain and Northern Ireland

Year of first data collection
1990

Primary Institutions

University of Bristol

Links

bristol.ac.uk/alspac/

cataloguementalhealth.ac.uk/

bristol.ac.uk/alspac/researchers/our-data/

doi.org/10.12688/wellcomeopenres.15132.1

Profile paper DOI

doi.org/10.1093/ije/dys064

Funders

Medical Research Council (MRC)

University of Bristol

Wellcome Trust

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
qualitativeData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-completed questionnaire – unspecified
Qualitative data collection
  • Interviews or focus groups
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
  • Magnetoencephalography (MEG)
Linked or secondary data
  • Education data
  • Geographic, spatial & environmental data
  • Healthcare data
  • Social media & technology use data
Features

Engagement

  • Community engagement
  • Patients, service users, lived experience involvement
  • Participant or community advisory groups
  • Keywords

    Biological samples/biospecimens
    Diet and nutrition
    Education
    Environmental exposures
    Ethnicity
    Family environment and factors
    Human development
    Infant biosamples
    Mental health
    Sexuality and gender identity
    Socioeconomics

    Consortia and dataset groups

    Catalogue of Mental Health Measures
    EU Child Cohort Network
    European Longitudinal Study of Pregnancy and Childhood (ELSPAC)
    FAMILY Consortium
    International Childhood Cancer Cohort Consortium (I4C)
    LongITools
    Methylation, Imaging and NeuroDevelopment (MIND) Consortium
    Pregnancy And Childhood Epigenetics (PACE) Consortium
    Study Team for Early Life Asthma Research (STELAR) consortium
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