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10/66 Dementia Research Group Population-Based Cohort Study - Mexico (10/66 Mexico)
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Sample details

The 10/66 Dementia Research Group Population-Based Cohort Study investigates the lives of older people in 8 study sites in low and middle-income countries with the aim of providing evidence for policy development and reform. Beginning in 2005, 10/66 Mexico recruited participants aged at least 65 years old from two locales: a rural location in Morelos State in south-central Mexico and urban Mexico City. Over 2,000 adults participated in the baseline data collection sweep between 2005 and 2006. Approximately half of the sample came from the rural locale and half from the urban locale. Participants were followed up between 2009 and 2010 and again between 2015 and 2016.

Study design
Cohort

Number of participants at first data collection

2,003 (participants)

Age at first data collection

≥ 65 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Older and elderly people
Population-based sample
Rural populations
Urban populations
Dataset details

Country

Mexico

Year of first data collection

2005

Primary Institutions

King's College London (KCL) (Academic, United Kingdom)

National Institute of Neurology and Neurosurgery (Instituto Nacional de Neurología y Neurocirugía, INNN) (Healthcare/Medical, Mexico)

Links

1066.alzint.org/

maelstrom-research.org/study/dementia-research-group

doi.org/10.1093%2Fije%2Fdyw056

unsw.edu.au/content/dam/pdfs/medicine-health/cheba/consortia/cosmic/2025-07-10_66-Mexico-Centre-for-Healthy-Brain-Ageing-CHeBA.pdf

Funders

Alzheimer's Association (Third Sector, United States of America)

Alzheimer's Disease International (ADI) (Third Sector, United Kingdom)

Wellcome Trust (Third Sector, United Kingdom)

Ongoing?
No

Data types collected

mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • None
Features

Engagement

  • Community engagement
  • Keywords

    Ageing
    Alzheimer's disease (AD)
    Biological samples/biospecimens
    Dementia
    Longstanding illness and disability
    Mild cognitive impairment (MCI)
    Noncommunicable diseases

    Consortia and dataset groups

    10/66 Dementia Research Group Cohort
    Ageing Trajectories of Health – Longitudinal Opportunities and Synergies (ATHLOS)
    Cohort Studies of Memory in an International Consortium (COSMIC)
    Global Alzheimer’s Association Interactive Network (GAAIN)
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