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A longitudinal study of brain development in children with autism
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Sample details

This study investigates the maturation of the resting-state peak alpha frequency and optic radiation white-matter in children with and without autism spectrum disorder (ASD). From 2016, the study recruited and assessed children with ASD and typically developing children aged 6 to 9 years, around 70 children per group, with a total of 142 participants. The first follow-up was conducted on average 19 months after baseline, and the second follow-up on average 21 months after the first follow-up.

Study design
Cohort, Cohort - birth

Number of participants at first data collection

142 (participants)

Age at first data collection

6 - 9 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Autism Spectrum Disorder (ASD)
Children and young people
Typically developing
Dataset details

Country

United States of America

Year of first data collection

2016

Primary Institutions

Children's Hospital of Philadelphia (CHOP)

Links

nda.nih.gov/edit_collection.html

reporter.nih.gov/project-details/9052396

doi.org/10.1007/s10803-023-05926-7

Funders

National Institute for Child Health and Human Development (NICHD)

National Institute of Mental Health (NIMH)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Audio or visual recordings (e.g. of child behaviour, facial expressions)
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Magnetic Resonance Imaging (MRI)
  • Magnetoencephalography (MEG)
Linked or secondary data
  • Healthcare data
Features

Engagement

  • None
  • Keywords

    Autism and Autism-like conditions
    Brain development
    Brain functioning
    Human development
    Neuroimaging
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