African American Clinical Core (AACORE)
AACORE investigates transitions from normal ageing to mild cognitive decline (MCI) and dementia in African American populations in the United States of America. The study recruits participants who self-identify as African American and are aged at least 65 years from Chicago, Illinois and its surrounding area. Participants with and without dementia are welcomed into the study. Between 2008 and 2009, 132 participants enrolled in the study. As of 2024, the study includes over 400 participants. As part of the study, participants are given the option to consent to brain donation after death. As of 2024, 84 autopsies of donated brains have been conducted.
Study design
Cohort
Number of participants at first data collection
403 (participants as of 2024)
Recruitment is ongoing
Age at first data collection
≥ 65 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2008
Primary Institutions
Rush University Medical Center (Rush)
Profile paper DOI
Not available
Funders
National Institute on Aging (NIA)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Passive electronic data collection (e.g. screen time, scroll speed)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- None
- Magnetic Resonance Imaging (MRI)
- Healthcare data
Engagement
Keywords
