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Effects of TBI & PTSD on Alzheimer's Disease in Vietnam Vets (ADNIDOD)
Effects of TBI & PTSD on Alzheimer's Disease in Vietnam Vets logo
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Sample details

ADNIDOD investigated the effects of traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) on Alzheimer's disease in veterans of the Vietnam War. Participants were Vietnam War veterans between 60 and 80 years old who had received a diagnosis of TBI or PTSD without mild cognitive impairment (MCI) or dementia. A group of participants without TBI or PTSD was also recruited as age-matched controls. At baseline over 450 participants were included in the study. Participants were followed up at 6 and 12 months.

Study design
Cohort - occupational

Number of participants at first data collection

463 (participants)

Age at first data collection

60 - 80 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Injured in combat
Veterans
Dataset details

Country

United States of America

Year of first data collection

2012

Primary Institutions

United States Department of Veterans Affairs (VA)

University of California, San Francisco (UCSF)

Links

adni.loni.usc.edu/about/related-collaborative-studies/

Funders

Alzheimer's Disease Neuroimaging Initiative (ADNI)

Department of Defense (DoD)

Foundation for the National Institutes of Health (FNIH)

National Institute of Biomedical Imaging and Bioengineering (NIBIB)

National Institute on Aging (NIA)

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
  • Positron Emission Tomography (PET)
Linked or secondary data
  • Employer data
Features

Engagement

  • Community engagement
  • Keywords

    Alzheimer's disease (AD)
    Anthropometry
    Biological samples/biospecimens
    Cognitive ageing and decline
    Cognitive function
    Neurocognition
    Trauma

    Consortia and dataset groups

    ADataViewer
    Global Alzheimer’s Association Interactive Network (GAAIN)
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