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Adult Health Study (AHS)
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Sample details

The AHS investigates the relationship between radiation exposure level, disease occurrence, and variation in physiological and biochemical determinants among the survivors of the atomic bombings of Hiroshima and Nagasaki, Japan. Since 1958, the study has followed around 20,000 atomic bomb survivors, selected from the Life Span Study (LSS) cohort. In 1977, around 2,400 LSS participants and 1,000 in utero-exposed individuals were added to the AHS study. In 2008, around 2,000 LSS participants who were exposed before the age of 10 years old were enrolled in the AHS study. Participants have been followed through biennial health examinations. A subset of participants enrolled in the Ni-Hon-San Study in 1965 to 1966.

Study design
Cohort

Number of participants at first data collection

19,961 (1958 cohort)

3,400 (1977 cohort)

2,000 (2008 cohort)

Age at first data collection

Varied (1958 cohort)

Varied (1977 cohort)

Varied (2008 cohort)

Participant year of birth

Varied (1958 cohort)

Varied (1977 cohort)

Varied (2008 cohort)

Participant sex
All

Representative sample at baseline?
No

Sample features

Atomic bomb survivors
Dataset details

Country

Japan

Year of first data collection

1958 (1958 cohort)

1977 (1977 cohort)

2008 (2008 cohort)

Primary Institutions

Radiation Effects Research Foundation (放射線影響研究所, RERF)

Links

rerf.or.jp/en/programs/research_activities_e/outline_e/progahs-en/

doi.org/10.3995/jstroke.31.439

doi.org/10.1136/bmjopen-2011-000654

Profile paper DOI
Not available

Funders

Department of Energy (DOE)

Ministry of Health, Labor and Welfare (厚生労働省, MHLW)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • Computerized tomography (CT)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Existing research data
  • Healthcare data
  • Mortality data
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Cancer
    Cardiovascular health and disease
    Disease
    Environmental exposures
    Liver disease
    Medical history
    Physical health
    Radiation exposure
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