The Adventist Religion & Health Study began in 2006, aiming to examine which aspects of religion account for better or worse health, as well as biopsychosocial pathways to health. The study was divided into two sub-studies: the Psychosocial Manifestations of Religion Sub-study (PsyMRS), and the Biological Manifestations of Religion Sub-study (BioMRS). Combined, the sub-studies included over 10,500 Seventh-day Adventists from the Adventist Health Study-2, from all 50 states in the United States of America, and Canada. Participants were first examined across 2006 and 2007 and were followed up again in 2009, with a second clinic run for BioMRS participants in 2010 and 2011.