AIDS Linked to the Intravenous Experience study (ALIVE)
The ALIVE study was designed to characterise the incidence and natural history of human immunodeficiency virus (HIV) infection among people who inject drugs in Baltimore, United States of America. Historically, the ALIVE Study operated as two components, titled ALIVE I and ALIVE II, which were combined in November 2019. Over 4,500 participants were recruited using community outreach across multiple waves from 1988 to 2023. Participants are followed up every 6 months and undergo blood collection, questionnaires, health assessments and HIV testing at each visit. There are a number of sub-studies associated with ALIVE.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
4,671 (participants)
Age at first data collection
Varied (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1988
Primary Institutions
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University (JHU)
Links
publichealth.jhu.edu/aids-linked-to-the-intravenous-experience/about-alive
Profile paper DOI
Funders
National Institute on Drug Abuse (NIDA)
National Institutes of Health (NIH)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – paper or computer assisted
- None
- None
- Mortality data
Engagement
Keywords
Consortia and dataset groups
