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All of Us Research Program
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Sample details

All of Us is a research program that aims to follow the health and outcomes of over one million participants residing in a state or territory of the United States of America, including populations that have historically been underrepresented in biomedical research. Between inception in 2018 and as of 2024, the database of the research program has enrolled more than 800,000 individuals from all 50 states and 3 territories; since 2023, the age criteria expanded from 18 years to also include children. Of the participants who have completed all of the steps of the initial protocol, more than 75% are from underrepresented populations, including around 50% from racial and ethnic minority groups.

Study design
Cohort - open

Number of participants at first data collection

800,000 (participants)

Recruitment is ongoing

Age at first data collection

Varied (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Under-represented groups
Dataset details

Country

United States of America

Year of first data collection

2018

Primary Institutions

National Institutes of Health (NIH)

Links

researchallofus.org/

allofus.nih.gov/

Funders

National Institutes of Health (NIH)

Ongoing?
Yes

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – online
  • Wearable devices
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Geographic, spatial & environmental data
  • Healthcare data
Features

Engagement

  • Participant or community advisory groups
  • Community engagement
  • Keywords

    Biological samples/biospecimens
    Electronic health records
    Genetics
    Health and wellbeing
    Healthcare access and use
    Lifestyle factors
    Mental health
    Physical health
    Wearables
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