Adolescent Master Protocol (AMP)
AMP is a prospective cohort study designed to evaluate the impact of human immunodeficiency virus (HIV) infection and antiretroviral treatment (ART) on perinatally-infected youth between the ages of 7 and 16 years. AMP enrolled 451 perinatally HIV-infected (PHIV+) children and adolescents and 227 perinatally HIV-exposed uninfected (PHEU) youth receiving care at 15 sites in the United States, including Puerto Rico. The study population was divided into four birth cohorts (1991–1993, 1994–1995, 1996–1997, and 1998–2002). AMP is a component of the Pediatric HIV/AIDS Cohort Study (PHACS).
Study design
Cohort - clinical
Number of participants at first data collection
188 (youth with perinatally acquired HIV)
29 (youth with perinatal HIV exposure)
197 (caregivers)
Age at first data collection
7 - 16 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2007
Primary Institutions
Harvard University
Tulane University
Profile paper DOI
Funders
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
Ongoing?
No
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Secondary data
- Self-report questionnaire – unspecified
- None
- None
- Existing research data
- Healthcare data
Engagement
Keywords
Consortia and dataset groups
