ANMerge
The AddNeuroMed consortium conducted a longitudinal observational cohort study with the aim to discover Alzheimer’s disease (AD) biomarkers. During this study, a broad selection of data modalities was measured, including clinical assessments, magnetic resonance imaging (MRI), genotyping, transcriptomic profiling, and blood plasma proteomics. Data collection was performed at six different centers across Europe: University of Kuopio, Finland; Aristotle University of Thessaloniki, Greece; King’s College London, United Kingdom; University of Lodz, Poland; University of Perugia, Italy; and University of Toulouse, France. ANMerge includes multimodal data from over 1,700 study participants across these six centers, with an average age of 76.4 years at baseline and 59% females. Data on 4,585 individual participant visits are included.
Study design
Cohort - clinical
Number of participants at first data collection
1,702 (participants)
Age at first data collection
≥ 65 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2005
Primary Institutions
Aristotle University of Thessaloniki (Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης, ΑΠΘ, AUTh)
King's College London (KCL)
University of Kuopio (now known as University of Eastern Finland, Itä-Suomen yliopisto)
University of Oxford
University of Perugia (Università degli Studi di Perugia)
Links
No website available
Profile paper DOI
Funders
Alzheimer's Research UK
European Federation of Pharmaceutical Industries and Associations (EFPIA)
European Union FP7 programmes
King's College London (KCL)
Medical Research Council (MRC)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- None
- Magnetic Resonance Imaging (MRI)
- Magnetic Resonance Spectroscopy (MRS)
- Existing research data
Engagement
Keywords
Consortia and dataset groups
