Advantageous Predictors of Acute Coronary Syndromes Evaluation Study (APACE)
The APACE study aims to investigate methods to improve the speed of detection or exclusion of acute myocardial infarction in patients presenting with acute chest pain to the emergency department. Since 2007, the study has recruited adults with acute chest pain within the last 12 hours who present to the emergency departments in 13 hospitals in Switzerland, Italy, the Czech Republic, Poland, and Spain. As of 2025, 10,000 participants have been recruited into the study. The APACE study continues to recruit, and participants are followed up via telephone at 6, 12, 24 and 60 months after recruitment.
Study design
Cohort - clinical, Cohort
Number of participants at first data collection
10,000 (participants as of 2025)
Recruitment is ongoing
Age at first data collection
≥ 18 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2007
Primary Institutions
Hospital Clinic of Barcelona (Hospital Clínico de Barcelona)
Hospital of the Sea (Hospital del Mar)
Kantonsspital Baselland, Standort Bruderholz
Kantonsspital Baselland, Standort Liestal
Kantonsspital Olten
Profile paper DOI
Funders
Swiss National Science Foundation (SNSF)
University Hospital of Basel (Universitätsspital Basel, USB)
Ongoing?
Yes
Data types collected
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- None
- None
- None
Engagement
Keywords
