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Advancing Understanding of RecOvery afteR trauma (AURORA)
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Sample details

The AURORA study aims to improve the prevention, diagnosis, and treatment of adverse posttraumatic neuropsychiatric sequelae following trauma. Participants include almost 4,000 individuals aged 18 to 75 years who present to the emergency department within 72 hours of a trauma experience at one of 23 participating sites across the United States of America. Beginning in 2017, participants have undergone a baseline evaluation in the emergency department, including blood collection and psychophysical, survey, and neurocognitive evaluation. They are then monitored for 8 weeks using a wearable device, smartphone app, daily surveys, online neurocognitive tests, saliva and blood collection, neuroimaging and psychophysical evaluation. Further follow-up occurs at three, six, nine and 12 months after baseline.

Study design
Cohort, Cohort - clinical

Number of participants at first data collection

3,829 (participants, as of 2021)

Recruitment is ongoing

Age at first data collection

18 - 75 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Trauma patients
Trauma survivors
Dataset details

Country

United States of America

Year of first data collection

2017

Primary Institutions

University of North Carolina at Chapel Hill (UNC)

Links

med.unc.edu/itr/aurora-study/

reporter.nih.gov/project-details/10021207

rti.org/impact/aurora-longitudinal-assessment-post-traumatic-syndromes

Funders

MAYDAY Fund

National Institute of Mental Health (NIMH)

National Institutes of Health (NIH)

One Mind

United States Army Medical Research and Development Command (USAMRDC)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Activity log (e.g. food, sleep, exercise)
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Passive electronic data collection (e.g. screen time, scroll speed)
  • Physical environment assessment (e.g. pollution, mould)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – online
  • Self-report questionnaire – unspecified
  • Wearable devices
Qualitative data collection
  • None
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Digital technology and social media
    Hospital admissions
    Neuroimaging
    Neuropsychological testing
    Pain
    Physical trauma
    Post-traumatic stress disorder (PTSD)
    Trauma
    Wearables

    Consortia and dataset groups

    Grady Trauma Project (GTP)
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