The AURORA study aims to improve the prevention, diagnosis, and treatment of adverse posttraumatic neuropsychiatric sequelae following trauma. Participants include almost 4,000 individuals aged 18 to 75 years who present to the emergency department within 72 hours of a trauma experience at one of 23 participating sites across the United States of America. Beginning in 2017, participants have undergone a baseline evaluation in the emergency department, including blood collection and psychophysical, survey, and neurocognitive evaluation. They are then monitored for 8 weeks using a wearable device, smartphone app, daily surveys, online neurocognitive tests, saliva and blood collection, neuroimaging and psychophysical evaluation. Further follow-up occurs at three, six, nine and 12 months after baseline.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
3,829 (participants, as of 2021)
Recruitment is ongoing
Age at first data collection
18 - 75 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2017
Primary Institutions
University of North Carolina at Chapel Hill (UNC)
Links
reporter.nih.gov/project-details/10021207
rti.org/impact/aurora-longitudinal-assessment-post-traumatic-syndromes
Profile paper DOI
Funders
MAYDAY Fund
National Institute of Mental Health (NIMH)
National Institutes of Health (NIH)
One Mind
United States Army Medical Research and Development Command (USAMRDC)
Ongoing?
Yes
Data types collected


Engagement
Keywords
Consortia and dataset groups