Breast Cancer Family Registry Cohort (BCFR)
The BCFR is a multi-center prospective cohort comprised of over 30,000 women and men from nearly 12,000 families from the United States, Canada, and Australia. BCFR aims to facilitate research investigating new ways to prevent, diagnose, and treat cancer. Participants were recruited from six international research sites and included people with breast cancer or a family history of breast cancer, their relatives and healthy controls. There have been several follow-ups since initial baseline data collection from 1996 to 2011 and three sub-studies associated with the cohort: Young Women’s Study, ProF-SC: Prospective Family Study Cohort, and the LEGACY Girls Study.
Study design
Cohort - open, Registry
Number of participants at first data collection
32,726 (participants)
Recruitment is ongoing
Age at first data collection
Varied (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
1996
Primary Institutions
Columbia University (Academic, United States of America)
Lunenfeld-Tanenbaum Research Institute (LTRI) (Research, Canada)
Stanford University (Academic, United States of America)
Temple University (Academic, United States of America)
University of Melbourne (Academic, Australia)
Profile paper DOI
Funders
National Cancer Institute (NCI) (Government, United States of America)
National Institutes of Health (NIH) (Government, United States of America)
U.S. Department of Health and Human Services (DHHS) (Government, United States of America)
Ongoing?
Yes
Data types collected
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-completed questionnaire – online
- Self-completed questionnaire – unspecified
- None
- None
- Healthcare data
- Mortality data
Engagement
Keywords
Consortia and dataset groups
