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Brazilian High Risk Cohort Study (BHRC)
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Sample details

The BHRC is designed to understand the developmental trajectories of psychopathology and mental disorders. The study recruited children born between 1998 and 2004 living in Brazil through public schools in Sao Paolo and Porto Alegre. Close to 10,000 children were screened for family history of mental health conditions, from which a sample, aimed to be representative of the community, and a high-risk sample of children based on their parents’ history of a mental health condition, were selected. This resulted in over 2,500 participants at inception.

Study design
Cohort

Number of participants at first data collection

2,511 (participants)

Age at first data collection

6 - 12 years (participants)

Participant year of birth

1998 - 2004 (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Children and young people
Community-based sample
High-risk populations
Dataset details

Country

Brazil

Year of first data collection

2009

Primary Institutions

Federal University of Rio Grande do Sul (Universidade Federal do Rio Grande do Sul, UFRGS)

University of São Paulo (Universidade de São Paulo, USP)

Links

osf.io/ktz5h/wiki/Study%20Design/

Funders

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Brazilian National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – online
Qualitative data collection
  • None
Neuroimaging data collection
  • Diffusion Tensor Imaging (DTI)
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • Community engagement
  • Keywords

    Cognition
    Genetic predisposition
    Human development
    Mental health
    Neuroimaging
    Parental mental health
    Psychiatry
    Psychology and psychopathology

    Consortia and dataset groups

    Methylation, Imaging and NeuroDevelopment (MIND) Consortium
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