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Biomarkers For Identifying Neurodegenerative Disorders Early and Reliably (BioFINDER One)
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Sample details

BioFINDER One was designed to investigate the etiologies of Alzheimer's disease, Parkinson's disease, and related disorders. The study sample includes elderly people fluent in Swedish with mild cognitive impairment from two memory clinics in southern Sweden, as well as cognitively healthy elderly people fluent in Swedish from the Malmö Diet and Cancer Study. This resulted in a baseline cohort of over 1,100 participants aged between 60 and 80 years.

Study design
Cohort

Number of participants at first data collection

1,150 (participants)

Age at first data collection

60 - 80 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Older and elderly people
Patients and clinical populations
Dataset details

Country

Sweden

Year of first data collection

2009

Primary Institutions

Lund University (Lunds Universitet)

Skåne University Hospital (Skånes universitetssjukhus, SUS)

Links

biofinder.se/one/

clinicaltrials.gov/study/NCT01208675

doi.org/10.1093/gerona/glaa143

Profile paper DOI
Not available

Funders

Crafoord Foundation

Region Skåne

Skåne University Hospital Foundation

Swedish Alzheimer Foundation (Alzheimerfonden)

Swedish Brain Foundation (Hjärnfonden)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • Arterial Spin Labelling (ASL)
  • Diffusion Tensor Imaging (DTI)
  • Functional magnetic resonance imaging (fMRI)
  • Magnetic Resonance Imaging (MRI)
  • Positron Emission Tomography (PET)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Alzheimer's disease (AD)
    Biological samples/biospecimens
    Biomarkers
    Cognitive ageing and decline
    Dementia
    Neuroimaging
    Parkinson's disease (PD)

    Consortia and dataset groups

    BioFINDER
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