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BIOMarker study to identify the Acute risk of a Coronary Syndrome (BIOMArCS)
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Sample details

BIOMArCS was an observational study designed to investigate the longitudinal biomarker patterns in patients admitted for an acute coronary syndrome (ACS). The study enrolled 844 patients aged 40 years and older who were admitted with an ACS in 18 hospitals across the Netherlands from 2008 to 2015. Blood samples were collected from the patients at admission, at the day of hospital discharge and subsequently every fortnight during the first 6 months after discharge, followed by monthly blood sample collection until 1 year.

Study design
Cohort - clinical, Cohort

Number of participants at first data collection

844 (participants)

Age at first data collection

≥ 40 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Older and elderly people
Patients and clinical populations
Dataset details

Country

Netherlands

Year of first data collection

2008

Primary Institutions

Erasmus University Medical Centre (Erasmus MC)

Links
No website available

Profile paper DOI

doi.org/10.1136/bmjopen-2016-012929

Funders

Dutch Heart Foundation (Hartstichting)

Eli Lilly, the Netherlands

Netherlands Heart Institute-Interuniversity Cardiology Institute of the Netherlands

Working Group of Cardiovascular Research Netherlands

Ongoing?
No

Data types collected

dataLinkage
Quantitative data collection
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Biomarkers
    Cardiovascular health and disease
    Clinical outcomes
    Heart disease and conditions
    Inflammation
    Inflammatory markers
    Medical history
    Predictors
    Risk factors
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