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Clinical Biological and Pharmacological Factors Influencing Stroke Outcome (BIOSTROKE)
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Sample details

This study tested the hypothesis that chronic excessive consumption of ethanol is associated with a higher severity of the neurological deficit in acute ischemic stroke. Patients with ischemic, hemorrhagic, or hemispheric stroke within 48 hours of symptom onset admitted to Lille University Hospital, France, were recruited for the BIOSTROKE study. A total of 477 patients were included, with a median age of 70 years and 47.0% being women. Patients completed a follow-up examination 8 and 90 days after admission, and 210 patients were then reviewed or assessed by phone 5 years later.

Study design
Cohort - clinical

Number of participants at first data collection

477 (participants)

Age at first data collection

53 - 80 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Patients and clinical populations
Stroke patients
Dataset details

Country

France

Year of first data collection

2005

Primary Institutions

Lille University Hospital

L’Institut national de la santé et de la recherche médicale (Inserm)

Links

cheba.unsw.edu.au/consortia/strokog/studies/clinical-biological-and-pharmacological-factors-influencing-stroke-outcome-biostroke

classic.clinicaltrials.gov/ct2/show/record/NCT00763217

Funders

Programme Hospitalier de Recherche Clinique (PHRC)

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • Computerized tomography (CT)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Cardiovascular health and disease
    Clinical assessments
    Clinical outcomes
    Cognitive assessments
    Cognitive impairment and disorders
    Dementia
    Neurodegeneration
    Pharmacological factors
    Post-stroke

    Consortia and dataset groups

    Stroke and Cognition consortium (STROKOG)
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