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Breakthrough Generations Study
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Sample details

The Breakthrough Generations Study is a large, comprehensive scientific study of the causes of breast cancer, and follows over 110,000 women from across the United Kingdom. The study participants are volunteers aged 16-102 years at recruitment, represent a broad geographic and socioeconomic distribution and many are biologically related to one another. It is intended that follow-up questionnaires will continue for the next 40 years and longer.

Study design
Cohort

Number of participants at first data collection

112,049 (participants)

Age at first data collection

≥ 16 years (participants)

Participant year of birth

Varied (participants)

Participant sex
Female

Representative sample at baseline?
No

Sample features

Intergenerational
Women
Dataset details
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Countries

England, Northern Ireland, Scotland, United Kingdom of Great Britain and Northern Ireland, Wales

Year of first data collection

2004

Primary Institutions

Institute of Cancer Research (ICR)

Links

thegenerationsstudy.co.uk/

breastcancernow.org/breast-cancer-research/research-projects/our-research-projects/breast-cancer-now-generations-study

Funders

Brazilian National Council for Scientific and Technological Development (Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq)

The Institute of Cancer Research (ICR)

Ongoing?
Yes

Data types collected

Quantitative data collection
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – paper or computer assisted
  • Wearable devices
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • None
Features

Engagement

  • Community engagement
  • Keywords

    Breast cancer
    Disease risk
    Gene-environment interactions (GxE)
    Protective factors
    Risk factors
    Women's health
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