Cardiovascular Risk Factors, Aging and Dementia (CAIDE)
The CAIDE study investigates the lifestyle and cardiovascular risk factors for dementia, Alzheimer's disease (AD) and structural brain changes in Eastern Finland. The cohort comprises Finnish individuals who participated in previous surveys (North Karelia project and FINMONICA/FINRISK study) between 1972 and 1987, during midlife. In 1998, approximately 1,500 individuals (aged 64 to 79 years) participated in a first re-examination as part of the CAIDE study. A second re-examination was conducted between 2005 and 2008. Between 2006 and 2009, a second cohort of almost 300 participants who also participated in the previous surveys was enrolled and assessed. The third follow-up (CAIDE 85+) was conducted between 2019 and 2021, assessing both samples. Participants are continuously followed up through linkage to national registers.
Study design
Cohort
Number of participants at first data collection
1,449 (cohort 1)
268 (cohort 2)
Age at first data collection
64 - 79 years (cohort 1)
Varied (cohort 2)
Participant year of birth
Varied (cohort 1)
Varied (cohort 2)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1998 (cohort 1)
2006 (cohort 2)
Primary Institutions
Finnish Institute for Health and Welfare (Terveyden ja hyvinvoinnin laitos, THL)
Karolinska Institute (Karolinska Institutet, KI)
University of Eastern Finland
Links
thl.fi/en/research-and-development/research-and-projects/caide-
uefconnect.uef.fi/en/caide-cardiovascular-risk-factors-aging-and-dementia/
Profile paper DOI
Funders
Academy of Finland
Juho Vainio Foundation
Ministry of Education and Culture (Opetus- ja kulttuuriministeriö)
Sigrid Juselius Foundation
Yrjö Jahnsson Foundation
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – paper or computer assisted
- Interviews or focus groups
- Magnetic Resonance Imaging (MRI)
- Healthcare data
- Mortality data
Engagement
Keywords
