Childhood Allergy and the NeOnatal Environment (CANOE)
CANOE is a National Institutes of Health (NIH)/Environmental influences on Child Health Outcomes (ECHO)-supported multi-center birth cohort. The study was launched in January 2019 across four sites to determine how pre-, peri-, and post-natal factors influence development of recurrent wheezing and atopic dermatitis. Pregnant women were recruited from four academic medical centers in Detroit (Michigan), Madison (Wisconsin), Nashville (Tennessee), and St. Louis (Missouri), in the United States of America. At baseline, participants were expectant mothers aged 18 years or older who were planning to deliver at a study site or affiliated hospital, and the expected child had at least one biological parent or sibling with asthma, allergic rhinitis, or atopic dermatitis.
Study design
Cohort - birth, Cohort - primary caregiver and child
Number of participants at first data collection
482 (pregnant women)
416 (children)
Age at first data collection
Birth (children)
≥ 18 years (pregnant women)
Participant year of birth
Varied (pregnant women)
~2019 (children)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2019
Primary Institutions
Henry Ford Health
University of Wisconsin-Madison
Vanderbilt University (VU)
Washington University in St. Louis (WashU)
Links
reporter.nih.gov/project-details/10744839
doi.org/10.1016%2Fj.jaci.2021.12.065
henryford.com/-/media/files/henry-ford/hcp/research/canoe-timeline-and-data-we-collect.pdf
Profile paper DOI
Funders
National Institutes of Health (NIH)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Interview – phone
- Physical environment assessment (e.g. pollution, mould)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – online
- None
- None
- None
Engagement
Keywords
Consortia and dataset groups
