CBCS is a mega-cohort study and the first nationally based birth cohort study in China, which aims to investigate and prevent birth defects. Between 2017 and 2021, the study recruited pregnant women from 50 study sites across 17 provinces (Inner Mongolia, Liaoning, Hebei, Beijing, Tianjin, Shandong, Jiangsu, Henan, Shaanxi, Gansu, Sichuan, Yunnan, Guizhou, Hunan, Jiangxi, Guangdong and Hainan) in China, of Chinese nationality, between 6 to 13 weeks of gestation, who planned to attend the routine antenatal examination and deliver in the study site. Over 130,000 participants completed the baseline data collection. Participants were followed up at 20-23 weeks and 28-33 weeks of gestation as well as at delivery, pregnancy loss or termination.
Study design
Cohort, Cohort - birth
Number of participants at first data collection
132,386 (participants)
Recruitment is ongoing
Age at first data collection
Varied (participants)
Participant year of birth
Varied (participants)
Participant sex
Female
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2017
Primary Institutions
Capital Medical University (首都医科大学, CCMU) (Academic, China)
Links
No website available
Profile paper DOI
Funders
National Key Research and Development Program of China (NKRDP, 国家重点研发计划) (Government, China)
Ongoing?
Yes
Data types collected

Engagement
Keywords