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Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI)
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Sample details

The CENTER-TBI includes a core study and a registry. A total of 65 centres initiated patient enrollment. The core study was an observational and longitudinal cohort study of patients with all severities of traumatic brain injury (TBI), presenting between December 19, 2014, and December 17, 2017, to centres across Europe and Israel. The generalisability of the core study was assessed through comparison with the registry, which collected administrative data.

Study design
Registry, Cohort - clinical

Number of participants at first data collection

4,559 (core cohort study)

22,849 (registry participants)

Age at first data collection

Varied (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Brain injury patients
Patients and clinical populations
Dataset details
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Countries

Austria, Belgium, Bosnia and Herzegovina, Denmark, England

Year of first data collection

2014

Primary Institutions

Antwerp University Hospital (UZA)

Links

center-tbi.eu/

clinicaltrials.gov/show/NCT02210221

Funders

European Union FP7 programmes

Hannelore Kohl Stiftung

Integra LifeSciences Corporation

Neurotrauma Sciences

One Mind

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – online
Qualitative data collection
  • None
Neuroimaging data collection
  • Computerized tomography (CT)
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • Community engagement
  • Participant or community advisory groups
  • Patients, service users, lived experience involvement
  • Keywords

    Brain functioning
    Brain injury or damage
    Clinical cohort
    Cognitive impairment and disorders
    Neurobehavioural tests
    Neuroimaging
    Population differences
    Recovery
    Registry
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