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Characterize differences in sleep spindles between Clinical High Risk and healthy controls longitudinally
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Sample details

This study aimed to characterise differences in sleep spindles between healthy subjects and individuals at Clinical High Risk (CHR) for psychotic disorders and schizophrenia in the United States of America. From 2017, the study recruited 45 CHR participants and 45 healthy controls, and participants completed three assessments over a two-year period.

Study design
Cohort, Cohort - clinical

Number of participants at first data collection

45 (CHR participants)

45 (healthy controls)

Age at first data collection

Varied (CHR participants)

Varied (healthy controls)

Participant year of birth

Varied (CHR participants)

Varied (healthy controls)

Participant sex
All

Representative sample at baseline?
No

Sample features

Control participants
High-risk populations
Patients and clinical populations
Dataset details

Country

United States of America

Year of first data collection

2017

Primary Institutions

University of Pittsburgh

Links

doi.org/10.15154/84gm-kn79

reporter.nih.gov/project-details/10160958

doi.org/10.1038/s41386-020-00920-4

doi.org/10.1093/sleep/zsae053

doi.org/10.1016/j.psychres.2024.115756

Profile paper DOI
Not available

Funders

National Institute of Mental Health (NIMH)

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
Qualitative data collection
  • None
Neuroimaging data collection
  • Electroencephalography (EEG)
  • Magnetic Resonance Imaging (MRI)
  • Magnetic Resonance Spectroscopy (MRS)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Cognitive function
    Neuroimaging
    Psychosis and psychotic disorders
    Schizophrenia
    Sleep
    Working memory
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