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Child Health and Development Studies (CHDS)
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Sample details

The CHDS aims to investigate how health and disease are passed on between generations. Between 1959 and 1966, over 15,000 pregnant women who were members of the Kaiser Foundation Health Plan in California were recruited. Data was collected from mothers during pregnancy, and the CHDS has continued to follow these mothers and their offspring over multiple time points across development. Data collection is ongoing, and data is currently being collected from a third generation of participants (CHDS grandchildren). The CHDS is involved in a variety of sub-projects.

Study design
Cohort - intergenerational

Number of participants at first data collection

15,528 (pregnant women)

19,044 (babies)

Recruitment is ongoing

Age at first data collection

Varied (pregnant women)

Birth (babies)

Participant year of birth

Varied (pregnant women)

1959 - 1967 (babies)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adolescents
Children and young people
Families
Mother and child dyad
Mothers
Dataset details

Country

United States of America

Year of first data collection

1959

Primary Institutions

Public Health Institute (PHI) (Third Sector, United States of America)

Links

chdstudies.org/index.php

dash.nichd.nih.gov/study/8

Funders

Brigham and Women's Hospital (Healthcare/Medical, United States of America)

Congressionally Directed Medical Research Programs (CDMRP) (Government, United States of America)

Department of Defense (DoD) (Government, United States of America)

Department of the Army (Government, United States of America)

Escher Fund for Autism (Research, United States of America)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
qualitativeData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-completed questionnaire – paper or computer assisted
Qualitative data collection
  • Interviews or focus groups
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Healthcare data
  • Medical birth registry
  • Mortality data
  • Other government data
Features

Engagement

  • Participant or community advisory groups
  • Community engagement
  • Keywords

    Biological samples/biospecimens
    Early-life determinants
    Environmental determinants
    Family environment and factors
    Health determinants
    Human development
    Pregnancy
    Social conditions and environment
    Sub-studies
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