The CHDS aims to investigate how health and disease are passed on between generations. Between 1959 and 1966, over 15,000 pregnant women who were members of the Kaiser Foundation Health Plan in California were recruited. Data was collected from mothers during pregnancy, and the CHDS has continued to follow these mothers and their offspring over multiple time points across development. Data collection is ongoing, and data is currently being collected from a third generation of participants (CHDS grandchildren). The CHDS is involved in a variety of sub-projects.
Study design
Cohort - intergenerational
Number of participants at first data collection
15,528 (pregnant women)
19,044 (babies)
Recruitment is ongoing
Age at first data collection
Varied (pregnant women)
Birth (babies)
Participant year of birth
Varied (pregnant women)
1959 - 1967 (babies)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1959
Primary Institutions
Public Health Institute (PHI) (Third Sector, United States of America)
Profile paper DOI
Funders
Brigham and Women's Hospital (Healthcare/Medical, United States of America)
Congressionally Directed Medical Research Programs (CDMRP) (Government, United States of America)
Department of Defense (DoD) (Government, United States of America)
Department of the Army (Government, United States of America)
Escher Fund for Autism (Research, United States of America)
Ongoing?
Yes
Data types collected




Engagement
Keywords