Childhood Origins of Asthma study (COAST)
COAST aims to study the contribution of, and the interactions among, age, patterns of cytokine secretion and virus infections, with respect to the subsequent development of childhood asthma. Participants include 289 children at increased risk of developing asthma (at least one parent has allergies and/or asthma), recruited at birth in Madison, Wisconsin, United States of America. Baseline assessment was conducted at birth between 1998 and 2000. Nasopharyngeal mucus samples were collected at 2, 4, 6, 9, 12, 18, and 24 months, and during times of acute respiratory illness during the first three years of life. After three years, participants have been followed up annually.
Study design
Cohort, Cohort - birth
Number of participants at first data collection
289 (participants)
Age at first data collection
Birth (participants)
Participant year of birth
1998 - 2000 (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1998
Primary Institutions
University of Wisconsin-Madison
Profile paper DOI
Funders
National Institutes of Health (NIH)
Ongoing?
Yes
Data types collected
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- None
- None
- None
Engagement
Keywords
Consortia and dataset groups
