CHIldhoood MicrobiomE (CHIME)
CHIME is a multicenter, prospective cohort study of healthy infants’ respiratory microbiome. Participants include healthy infants who visited a primary care group practice from November 2013 to May 2014. Participants have in-person visits at approximate ages of 1, 2, 3, and 6 years in addition to telephone follow-up calls every 6 months. Study staff collect nasal swabs, saliva swabs, fecal samples, and blood at various time points. Relevant medical records are acquired from enrollment through age 6 years.
Study design
Cohort
Number of participants at first data collection
115 (participants)
Age at first data collection
~1 year (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2013
Primary Institutions
Massachusetts General Hospital (MGH)
Profile paper DOI
Funders
National Institutes of Health (NIH)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Interview – online
- Interview – phone
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- None
- None
- Healthcare data
Engagement
Keywords
Consortia and dataset groups
