Cooperative Health Research in South Tyrol study (CHRIS study)
The CHRIS cohort is an ongoing population-based study investigating genetic and lifestyle determinants of health and healthy aging in a cohort of 13,393 adults from the Val Venosta/Vinschgau district of South Tyrol, Italy. From 2011 to 2018, participants aged 18 years and older completed baseline assessments providing biological samples and a wide range of sociodemographic, behavioural, and clinical information, with a focus on cardiovascular, metabolic, neurologic, and psychiatric health. The first follow-up phase began in 2019 and is anticipated to continue until 2027. As of 2025, over 5,500 participants have completed a visit as part of ongoing follow-up, providing most of the same data and samples as at baseline. The CHRIS cohort includes 667 participants who previously took part in the Microisolates in South Tyrol (MICROS) study in 2002/3, thereby providing additional longitudinal data and biological samples for these participants.
Study design
Cohort, Biobank
Number of participants at first data collection
13,393 (participants)
Age at first data collection
18 - 94 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2011
Primary Institutions
Eurac Research Institute for Biomedicine
Healthcare System of the Autonomous Province of Bolzano-South Tyrol
Links
eurac.edu/en/institutes-centers/institute-for-biomedicine/pages/chris
Profile paper DOI
Funders
Department of Innovation, Research, University and Museums of the Autonomous Province of Bolzano-South Tyrol
European Regional Development Fund (ERDF)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – online
- Self-report questionnaire – paper or computer assisted
- Wearable devices
- None
- None
- Existing research data
Engagement
Keywords
Consortia and dataset groups
