Centre de Neurologie Cognitive study at Lariboisière Hospital (CNC)
The Centre de Neurologie Cognitive (CNC) cohort is a prospective observational clinic-based study conducted at Lariboisière Hospital in Paris, France. It includes 321 participants with cognitive disorders who were recruited from the hospital’s memory clinic between July 2, 2008, and June 15, 2017. Inclusion criteria required a full clinical workup at Lariboisière Hospital, cerebrospinal fluid (CSF) biomarker measurements, and a final clinical diagnosis. The cohort consists of individuals with Alzheimer’s disease (AD) and non-AD cognitive disorders, such as frontotemporal dementia, Parkinson’s disease, and vascular dementia. Patients underwent routine clinical, neurological, and neuropsychological evaluations, with brain imaging as needed. Follow-ups took place throughout the study period (2008–2017) as part of regular clinical care.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
321 (participants)
Age at first data collection
Varied (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2008 (participants)
Primary Institutions
Lariboisière Hospital (L'hôpital Lariboisière)
Paris Diderot University (now known as Paris Cité University, Université Paris Cité)
Links
Profile paper DOI
Funders
Agence Nationale de la Recherche (ANR)
Alzheimer Society of Canada
Alzheimer's Association
Assistance publique - Hôpitaux de Paris
Brain Canada Foundation (Fondation Brain Canada)
Ongoing?
No
Data types collected
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- None
- Magnetic Resonance Imaging (MRI)
- Healthcare data
Engagement
Keywords
