Chinese National Twin Cohort and Registry (CNTR)
The CNTR, established in 2001, aims to assess the interplay between genetic and environmental factors towards health outcomes, mainly focusing on cardiovascular health, through examining twins across China. Participants are from nine provinces within the country, including Beijing, Shanghai, Qingdao, and Lishui, collecting data from urban and rural areas. Initially, 7,423 twin pairs were recruited from 2001 to 2005 through local Centers for Disease Control and Prevention (CDCs), residence registries, and public media, primarily below 18 years old, with the cohort having grown significantly and follow-ups for adults occurring every 2.5 years.
Study design
Registry, Cohort - twin
Number of participants at first data collection
61,566 (twin pairs as of 2019)
Recruitment is ongoing
Age at first data collection
Varied (twin pairs)
Participant year of birth
Varied (twin pairs)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2001
Primary Institutions
Beijing Center for Disease Control and Prevention (疾病预防控制中心, CDC) (Government, China)
Dezhou Center for Disease Control and Prevention (疾病预防控制中心, CDC) (Government, China)
Handan Center for Disease Control and Prevention (邯郸市疾控中心, CDC) (Government, China)
Harbin Medical University (哈尔滨医科大学, HMU) (Academic, China)
Heilongjian agricultural area CDC (Government, China)
Profile paper DOI
Funders
China Medical Board (CMB) (Third Sector, United States of America)
National Natural Science Foundation of China (国家自然科学基金委员会, NSFC) (Government, China)
Special Fund for Health Scientific Research in Public Welfare (Government, China)
Ongoing?
Yes
Data types collected
- Interview – face-to-face
- Physical environment assessment (e.g. pollution, mould)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-completed questionnaire – paper or computer assisted
- None
- None
- None
Engagement
Keywords
Consortia and dataset groups
