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Cognitive Function After Stroke (CogFAST)
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Sample details

CogFAST aimed to examine changes in brain function following stroke. The study recruited over 350 older adults (aged 75 years and above) from stroke registers in Tyneside and Wearside, North East England, United Kingdom. Participants were eligible if they were within three months post-stroke, had no prior diagnosis of dementia or significant physical illness, and were able to provide informed consent. Baseline assessments took place between 1999 and 2003, with follow-ups conducted three months post-stroke and then annually for up to eight years. Magnetic resonance imaging (MRI) was performed at the three-month and two-year assessments. The study concluded in 2012.

Study design
Cohort, Cohort - clinical

Number of participants at first data collection

355 (participants)

Age at first data collection

≥ 75 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Older and elderly people
Patients and clinical populations
Stroke patients
Dataset details
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Countries

England, United Kingdom of Great Britain and Northern Ireland

Year of first data collection

1999

Primary Institutions

Newcastle University

Links

research.ncl.ac.uk/cogfast/home/

unsw.edu.au/content/dam/pdfs/medicine-health/cheba/consortia/strokog/2025-06-Cognitive-Function-After-Stroke-CogFAST-UK.pdf

unsw.edu.au/cheba/research-and-impact/consortia/strokog

doi.org/10.1093/brain/awr273

Funders

Alzheimer's Research UK

Alzheimer's Society

Medical Research Council (MRC)

Newcastle Centre for Brain Ageing and Vitality

Newcastle upon Tyne Hospitals NHS Foundation Trust

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-completed questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • Healthcare data
  • Mortality data
Features

Engagement

  • Participant or community advisory groups
  • Community engagement
  • Keywords

    Ageing
    Alzheimer's disease (AD)
    Biological samples/biospecimens
    Cognitive ageing and decline
    Dementia
    Elderly
    Neurological examination
    Neurology and neurological diseases
    Stroke

    Consortia and dataset groups

    Stroke and Cognition consortium (STROKOG)
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