Cognition, Brain, and Aging study (COBRA)
The COBRA study is a longitudinal research project based in Umeå, Sweden, that follows a cohort of 181 healthy older adults to investigate the relationships between brain structure and function, lifestyle, and cognitive ageing. Participants were randomly selected from the Swedish population registry in Umeå and recruited between 2012 and 2014. At recruitment, participants were aged 64 to 68 years, and only included those with no history of neurological/cardiovascular disease and no medication use. The cohort has completed three waves of data collection (2012-2014, 2017 and 2022), with follow-ups conducted at approximately five-year intervals.
Study design
Cohort
Number of participants at first data collection
181 (participants)
Age at first data collection
64 - 68 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2012
Primary Institutions
Umeå University (Umeå Universitet)
Profile paper DOI
Funders
German Research Foundation (Deutsche Forschungsgemeinschaft, DFG)
Knut and Alice Wallenberg Foundation
Max Planck Society
Swedish Brain Power
Swedish Research Council (Vetenskapsrådet)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- None
- Functional magnetic resonance imaging (fMRI)
- Magnetic Resonance Imaging (MRI)
- Positron Emission Tomography (PET)
- None
Engagement
Keywords
Consortia and dataset groups
