Cognitive-Affective Psychosis Proneness Risk and protective factors in 22q11.2 Deletion Syndrome
This study investigates how interactions between cognitive control and emotion regulation contribute to psychosis-proneness in adolescents with 22q11.2 deletion syndrome. It includes 107 participants aged 12 to 18 years (57 with 22q11.2DS, 50 typically developing), recruited from the UC Davis MIND Institute in California, United States of America, the surrounding community, as well as local and online advertising, with baseline data collection beginning in 2015. Participants are followed up approximately 2.5 years after their initial visit to assess longitudinal changes in neurocognitive and affective functioning.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
107 (participants)
Age at first data collection
12 - 18 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2015
Primary Institutions
University of California, Davis (UC Davis)
Profile paper DOI
Funders
National Institute of Mental Health (NIMH)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Self-report questionnaire – paper or computer assisted
- None
- Electroencephalography (EEG)
- Functional magnetic resonance imaging (fMRI)
- None
Engagement
Keywords
