Connectomics in Brain Aging and Dementia Project (CoBRA)
The CoBRA study aims to investigate the structural and functional changes in the brain associated with Alzheimer's disease (AD) and ageing, using multi-modal imaging techniques like MRI, fMRI, MEG, and in vivo amyloid imaging. So far, 270 participants aged 50 to 89 years have been recruited at the University of Pittsburgh Alzheimer's Disease Research Center in Pittsburgh, the United States of America. Baseline data collection began in 2016 and involved three days of initial assessment. The study plans to continue for six years, with follow-up visits every two years.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
270 (participants)
Recruitment is ongoing
Age at first data collection
50 - 89 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2016
Primary Institutions
University of Pittsburgh
Links
humanconnectome.org/study/connectomics-brain-aging-and-dementia
Profile paper DOI
Funders
National Institute on Aging (NIA)
National Institutes of Health (NIH)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – unspecified
- None
- Functional magnetic resonance imaging (fMRI)
- Magnetic Resonance Imaging (MRI)
- Magnetoencephalography (MEG)
- Positron Emission Tomography (PET)
- None
Engagement
Keywords
Consortia and dataset groups
