Copenhagen Prospective Studies on Asthma in Childhood 2000 (COPSAC2000)
The COPSAC2000 cohort is one of four prospective clinical cohort studies consisting of 411 children of asthmatic mothers. The study is designed to assess gene-environment interactions in the origin of atopic diseases with an aim to identify early-life exposures that can be modified to improve preventive strategies. The children attend the COPSAC clinical research unit from birth till adolescence at scheduled clinical investigations according to standard operating procedures. Additional visits are arranged at the onset of any respiratory or skin symptom. COPSAC recruited pregnant women from greater Copenhagen, Denmark. All mothers are fluent in Danish and possess a physician’s diagnosis of asthma and the need for daily treatment of asthma after the age of 7 years.
Study design
Cohort - clinical, Cohort - primary caregiver and child, Cohort - birth
Number of participants at first data collection
411 (children)
411 (mothers)
Age at first data collection
Birth (children)
Varied (mothers)
Participant year of birth
1998 - 2001 (children)
Varied (mothers)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1998
Primary Institutions
Copenhagen University Hospital (Rigshospitalet)
Profile paper DOI
Funders
Købmand Sven Hansen og Hustru Ina Hansens Fond
A.P. Møller Foundation for the Advancement of Medical Science
Aage Bangs Fond
Aase og Ejnar Danielsens Fond
Astma-Allergi Forbundet
Ongoing?
Yes
Data types collected
- Activity log (e.g. food, sleep, exercise)
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical environment assessment (e.g. pollution, mould)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Wearable devices
- None
- None
- Geographic, spatial & environmental data
- Healthcare data
Engagement
Keywords
Consortia and dataset groups
