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Copenhagen Prospective Studies on Asthma in Childhood Severe (COPSACSEVERE)
Copenhagen Prospective Studies on Asthma in Childhood Severe logo
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Sample details

The COPSACSEVERE cohort is a register-based cohort of children with asthma who were identified and characterized from national health registries across Denmark. This cohort comprises children with recurrent hospitalizations due to severe asthma exacerbations during the first 6 years of life. Children with repeated acute hospitalizations (cases) were identified in the Danish National Patient Register, covering all diagnoses of discharges from Danish hospitals. All participants had at least two acute hospitalizations for asthma from 2 to 6 years of age (both years included). The duration of hospitalization was more than 1 day for all participants, and two hospitalizations had to be separated by at least 6 months to be included in the cohort.

Study design
Biobank, Registry, Cohort - clinical

Number of participants at first data collection

1,204 (participants)

Recruitment is ongoing

Age at first data collection

2 - 6 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Children and young people
Patients and clinical populations
Dataset details

Country

Denmark

Year of first data collection

2021

Primary Institutions

Copenhagen University Hospital (Rigshospitalet)

Links

copsac.com/home/copsac-cohorts/copsac-severe-cohort/

doi.org/10.1016/j.jaci.2022.11.022

Profile paper DOI

doi.org/10.1038/ng.2830

Funders

Børnelungefonden

Lundbeck Foundation

Novo Nordisk Foundation

Ongoing?
Yes

Data types collected

dataLinkage
Quantitative data collection
  • Secondary data
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
Features

Engagement

  • Community engagement
  • Keywords

    Asthma
    Genetic predisposition
    Genetics
    Hospital admissions
    Hospital-based registry
    Medical history
    Medical records
    Respiratory health and disease

    Consortia and dataset groups

    COPSAC
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