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Cancer Prevention Study II (CPS-II)
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Sample details

The Cancer Prevention Studies (CPS) aim to understand why and how certain people develop cancer while others remain cancer-free. In 1982, the CPS-II cohort was established and includes approximately 1.2 million men and women, aged at least 30 years, recruited by American Cancer Society (ACS) volunteers in all 50 states of the United States of America and Puerto Rico. Participants have been followed biannually for mortality. The CPS-II Nutrition Cohort was established as a subgroup of the larger CPS-II cohort, in which approximately 185,000 individuals have been followed biennially for cancer incidence, diet, and other exposures, since 1992. The CPS-II Lifelink Cohort/Biorepository was initiated in 1998, and collected blood samples from 40,000 participants and cheek cell samples from 70,000 participants in the CPS-II Nutrition Survey cohort.

Study design
Cohort, Registry, Biobank

Number of participants at first data collection

1,184,881 (participants)

Age at first data collection

30 - 111 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Dataset details

Country

United States of America

Year of first data collection

1982

Primary Institutions

American Cancer Society (ACS)

Links

cancer.org/research/population-science/cancer-prevention-and-survivorship-research-team/acs-cancer-prevention-studies/cancer-prevention-study-2.html

epi.grants.cancer.gov/cohort-consortium/members/cps.html

cancer.org/research/population-science/cancer-prevention-and-survivorship-research-team/acs-cancer-prevention-studies.html

cancer.org/research/population-science/cancer-prevention-and-survivorship-research-team/acs-cancer-prevention-studies/cancer-prevention-questionnaires.html

doi.org/10.1002/cncr.10197

Profile paper DOI
Not available

Funders

American Cancer Society (ACS)

Ongoing?
Yes

Data types collected

dataLinkage
Quantitative data collection
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
  • Mortality data
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Cancer
    Cancer registry
    Demographics
    Diet and nutrition
    Family health history
    Hormones
    Lifestyle factors
    Lung cancer
    Medical history
    Physical activity and exercise
    Risk factors
    Smoking
    Sub-studies

    Consortia and dataset groups

    Cancer Prevention Study
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