Cognitive Health in Ageing Register: Investigational, Observational, and Trial studies in dementia research (CHARIOT): Prospective Readiness cOhort Study (PRO) Sub Study (CPSS)
CPSS aimed to characterise non-symptomatic Alzheimer's Disease (AD) and related cognitive impairments. Recruited participants were cognitively normal participants aged 60-85 from Greater London and Edinburgh. The cohort consists of elderly adults classified as high, medium, or low risk for developing mild cognitive impairment–Alzheimer's disease based on screening assessments. Over 1,000 participants completed the baseline data collection. Participants were followed up quarterly until the end of the study.
Study design
Cohort - clinical
Number of participants at first data collection
1,136 (participants)
Age at first data collection
60 - 85 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Countries
Year of first data collection
2015
Primary Institutions
Imperial College London (Imperial, ICL)
Janssen Pharmaceutical Research & Development LLC
University of Edinburgh (University o Edinburgh, Oilthigh Dhùn Èideann)
Profile paper DOI
Funders
Janssen Pharmaceutical Research & Development LLC
Ongoing?
No
Data types collected
- Activity log (e.g. food, sleep, exercise)
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – unspecified
- Wearable devices
- None
- Diffusion Tensor Imaging (DTI)
- Functional magnetic resonance imaging (fMRI)
- Magnetic Resonance Imaging (MRI)
- Positron Emission Tomography (PET)
- None
Engagement
Keywords
