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China Surgery and Anesthesia Cohort (CSAC)
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Sample details

The CSAC study aims to understand both the short- and long-term outcomes of patients undergoing elective surgeries with general anesthesia. Launched in 2020 with an initial cohort of over 10,000 participants from West China Hospital, the study has since expanded to include 12,766 participants across another three medical centers in China: the First People’s Hospital of Longquanyi District, West China Tianfu Hospital, and the Second Hospital of Hebei Medical University. Initially, the study focused on patients undergoing non-cardiac surgeries, with an expansion to include cardiac surgeries in July 2021. At baseline, participants consisted of 57.93% females, comparative to 42.03% males, with a mean age of 52.40 years. Follow-up assessments occur at 1, 3, and 7 days post-surgery and then at 1, 3, 6, and 12 months, with ongoing monitoring to gather comprehensive long-term data.

Study design
Cohort - open, Cohort - clinical

Number of participants at first data collection

10,692 (participants)

Recruitment is ongoing

Age at first data collection

40 - 65 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Middle-aged people
Surgery patients
Dataset details

Country

China

Year of first data collection

2020

Primary Institutions

Second Hospital of Hebei Medical University (二附院, Kotnis China-India Friendship Hospital)

West China Medical Center, Sichuan University (四川大学华西医学中心)

West China Tianfu Hospital

Links

biomedbdc.wchscu.cn/JoylabErasePM/hx-portals/

ouci.dntb.gov.ua/en/works/4z6YgeP4/

Funders

Key Research and Development Program of Science and Technology Department of Sichuan Province

National Natural Science Foundation of China (国家自然科学基金委员会, NSFC)

West China Hospital of Sichuan University

Ongoing?
Yes

Data types collected

mentalHealthData
dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Interview – phone
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – online
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Healthcare data
  • Mortality data
Features

Engagement

  • None
  • Keywords

    Biological determinants
    Biological samples/biospecimens
    COVID-19
    Clinical risk
    Gene-environment interactions (GxE)
    Lifestyle factors
    Neuropsychological testing
    Population health
    Post surgical outcomes
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