Cape Town Adolescent Antiretroviral Cohort (CTAAC)
CTAAC investigated markers of chronic disease processes and progression in perinatally human immunodeficiency virus (HIV)-infected adolescents on antiretroviral therapy (ART). Over 18 months from 2013, the study enrolled 515 HIV-infected adolescents on ART and 110 HIV-uninfected controls, aged 9 to 14 years, from eight sites around Cape Town, South Africa, as well as their caregivers. Participants were followed up every 6 months for 3 years.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
515 (HIV-infected participants)
110 (HIV-uninfected control participants)
121 (caregivers)
Age at first data collection
9 - 14 years (HIV-infected participants)
9 - 14 years (HIV-uninfected control participants)
Varied (caregivers)
Participant year of birth
Varied (HIV-infected participants)
Varied (HIV-uninfected control participants)
Varied (caregivers)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2013
Primary Institutions
University of Cape Town (iYunivesithi yaseKapa, Universiteit van Kaapstad, UCT)
Links
paediatrics.uct.ac.za/cape-town-adolescent-antiretroviral-cohort-study
doi.org/10.1007/s40653-021-00362-0
doi.org/10.1007/s13365-019-00792-5
Profile paper DOI
Not available
Funders
National Institute of Child Health & Human Development (NICHD)
South African Medical Research Council (SAMRC)
University of Cape Town (iYunivesithi yaseKapa, Universiteit van Kaapstad, UCT)
Ongoing?
No
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Interview – face-to-face
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Secondary data
- Self-report questionnaire – paper or computer assisted
- Qualitative survey
- Diffusion Tensor Imaging (DTI)
- Functional magnetic resonance imaging (fMRI)
- Healthcare data
Engagement
Keywords
