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Dutch Bipolar and Schizophrenia Offspring Study (DBSOS)
Dutch Bipolar and Schizophrenia Offspring Study  logo
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Sample details

The DBSOS aims to understand the development and risk of mental health conditions in children based on their parents' psychiatric history and to identify factors of risk and resilience. The study began in 2010, including over 200 participants in the Netherlands. Participants included offspring of parents with schizophrenia, offspring of parents with bipolar disorder, and control offspring. Follow-up assessments were conducted between 2014 and 2019, with 184 participants involved.

Study design
Cohort

Number of participants at first data collection

208 (participants)

Age at first data collection

8 - 18 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

At-risk offspring
Children and young people
Control participants
Dataset details

Country

Netherlands

Year of first data collection

2010

Primary Institutions

Erasmus University Medical Centre (Erasmus MC)

University Medical Center Utrecht (Universitair Medisch Centrum Utrecht, UMCU)

Links

bridge-onderzoek.nl/english/

doi.org/10.1016/j.bpsgos.2024.100336

Profile paper DOI

doi.org/10.1111/bdi.13351

Funders

Brain and Behavior Research Foundation (BBRF)

Dutch Research Council (Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO)

European Research Council (ERC)

European Union Horizon 2020 Research and Innovation Program

Ministry of Education, Culture and Science (Ministerie van Onderwijs, Cultuur en Wetenschappen, OCW)

Ongoing?
Yes

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – unspecified
Qualitative data collection
  • None
Neuroimaging data collection
  • Magnetic Resonance Imaging (MRI)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Adolescence
    Bipolar disorder
    Cognitive function
    Disease prevention
    Disease risk
    Environmental factors
    Family health history
    Gene-environment interactions (GxE)
    Mental health
    Neurocognition
    Neuroimaging
    Parental mental health
    Psychosis and psychotic disorders
    Risk factors
    Schizophrenia

    Consortia and dataset groups

    FAMILY Consortium
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