The DC was set up to study the determinants of complications in individuals with type 2 diabetes and examine the role of genetic, physiological, and lifestyle factors in the development of complications in these individuals. Participants include adult Singaporeans and permanent residents (aged 21 years and above) with physician-diagnosed type 2 diabetes. Individuals with mental illness, clinically-obvious non-diabetic kidney disease (such as polycystic kidney disease), type 1 diabetes, or diabetes mellitus resulting from endocrinopathies were not included. Data has been collected at 3 different timepoints: baseline, 2004 to 2010 (DC_T1); first follow-up, 2010 to 2016 (DC_T2); and second follow-up, 2016 to 2021 (DC_T3). The mean age of participants at baseline was 59.7 years, and 50.8% of participants were men. The ethnic composition was 59.3% Chinese, 22.7% Malay, and 17.3% Indian.
Study design
Cohort - clinical
Number of participants at first data collection
14,033 (participants)
Age at first data collection
≥ 21 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2004
Primary Institutions
National University Health System (NUHS)
National University of Singapore (NUS)
Profile paper DOI
Funders
Biomedical Research Council
Ministry of Health
National Medical Research Council (NMRC)
National University Health System (NUHS)
National University of Singapore (NUS)
Ongoing?
Yes
Data types collected
Engagement
Keywords
Consortia and dataset groups