The DC was established to investigate the determinants of complications in individuals with type 2 diabetes and to examine the roles of genetic, physiological, and lifestyle factors in the development of complications in these individuals. Participants include adult Singaporeans and permanent residents (aged 21 years and above) with physician-diagnosed type 2 diabetes. Individuals with mental illness, clinically-obvious non-diabetic kidney disease (such as polycystic kidney disease), type 1 diabetes, or diabetes mellitus resulting from endocrinopathies were not included. Data have been collected at three different timepoints: baseline (2004-2010, DC_T1); first follow-up (2010-2016, DC_T2); and second follow-up (2016-2021, DC_T3). The mean age of participants at baseline was 59.7 years, and 50.8% of participants were men. The ethnic composition of the sample was 59.3% Chinese, 22.7% Malay, and 17.3% Indian.
Study design
Cohort - clinical
Number of participants at first data collection
14,033 (participants)
Age at first data collection
≥ 21 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2004
Primary Institutions
National University Health System (NUHS)
National University of Singapore (NUS)
Profile paper DOI
Funders
Biomedical Research Council
Ministry of Health
National Medical Research Council (NMRC)
National University Health System (NUHS)
National University of Singapore (NUS)
Ongoing?
Yes
Data types collected


Engagement
Keywords
Consortia and dataset groups