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DOLORISK: Understanding Risk Factors and Determinants for Neuropathic Pain - Chronic Neuropathy Following Chemotherapy (DOLORisk)
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Sample details

DOLORisk is a multi-centre observational study that aims to understand the risk factors and determinants for neuropathic pain. Participant recruitment occurred between 2015 and 2019. The main longitudinal branch of the study consisted of 2 existing population cohorts: Generation Scotland (a family-based study) and GoDARTS (Genetics of Diabetes Audit and Research in Tayside Study—focused on diabetes), whose participants were contacted by the University of Dundee to be rephenotyped for neuropathic pain (approximately 9,000 respondents at baseline). Aarhus University and INSERM recruited smaller cohorts of participants scheduled to undergo chemotherapy, thoracic surgery, or breast cancer surgery.

Study design
Cohort - clinical

Number of participants at first data collection

No information found

Age at first data collection

≥ 18 years (participants)

Participant year of birth

Varied (participants)

Participant sex
All

Representative sample at baseline?
No

Sample features

Chronic pain patients
Dataset details
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Countries

Denmark, England, France, Scotland, United Kingdom of Great Britain and Northern Ireland

Year of first data collection

2016

Primary Institutions

Aarhus University Hospital (Aarhus Universitetshospital, AUH)

National Institute of Health and Medical Research (Institut National de la Santé et de la Recherche Médicale, INSERM)

Links

clinicaltrials.gov/show/NCT02654691

doi.org/10.1097/pr9.0000000000001086

Funders

European Union Horizon 2020 Research and Innovation Program

International Diabetic Neuropathy Consortium (IDNC)

Novo Nordisk Foundation

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • Electroencephalography (EEG)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Biological samples/biospecimens
    Cancer
    Chronic pain
    Physical health
    Surgery recovery
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