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Developmental origins of metabolic diseases: Pisa cohort (DORIAN-PISAC)
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Sample details

DORIAN-PISAC was a longitudinal research project based in Pisa, Italy, that investigated the relationship between maternal health, infant gut microbiota, and cognitive development. Between 2011 and 2014, 90 families were recruited during the first trimester of pregnancy or at delivery through hospital visits. At birth, data were collected from infants and parents, including parental intelligence assessments. Infants were then followed up at 6, 12, 18, 24, 36, and 60 months of age for assessments of cognitive development and microbiota composition.

Study design
Cohort, Cohort - birth

Number of participants at first data collection

90 (families)

Age at first data collection

Varied (parents)

Birth (children)

Participant year of birth

Varied (parents)

Varied (children)

Participant sex
All

Representative sample at baseline?
The population of Pisa, Italy.

Sample features

Families
Fathers
Mother and child dyad
Mother-father-baby triad
Mothers
Dataset details

Country

Italy

Year of first data collection

2011

Primary Institutions

Foundation IRCCS Stella Maris (IRCCS Fondazione Stella Maris)

National Research Council of Italy (Consiglio Nazionale delle Ricerche, CNR)

Links

mica.mdc-berlin.de/study/dorian

doi.org/10.3390/nu12082320

Funders

European Union FP7 programmes

European Union Horizon 2020 Research and Innovation Program

Genome Research Center for Health (Centro di Ricerca Genomica per la Salute)

National Research Council (Consiglio Nazionale delle Ricerche, CNR)

Ongoing?
No

Data types collected

dataLinkage
Quantitative data collection
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
  • Secondary data
  • Self-report questionnaire – paper or computer assisted
Qualitative data collection
  • None
Neuroimaging data collection
  • None
Linked or secondary data
  • Employer data
Features

Engagement

  • None
  • Keywords

    Anthropometry
    Cognitive assessments
    Family-based
    Gut health
    Lifecourse
    Maternal health
    Neurocognitive development
    Physical health assessments

    Consortia and dataset groups

    Intestinal Microbiomics Knowledge Platform (INTIMIC-KP)
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