The Dutch Hunger Winter Families study is the fifth of the Dutch famine birth cohort studies, following over 3,300 singleton births in three clinics in cities affected by the famine in 1944-1945. The cohort includes all 2,417 infants born between 1 February 1945 and 31 March 1946 born to mothers who were exposed to the famine during or immediately preceding that pregnancy, and a sample of 890 births from 1943 and 1947 of infants whose mothers did not experience famine during this pregnancy. In 2003, the members of the study were identified through birth records and traced to their current address, and a telephone interview and medical examination were conducted between 2003-2005.