Dynamic Inflammatory and Mood Predictors of Cognitive Aging in Bipolar Disorder
This study is part of the GAGE-BD project, which aims to study the trajectory of bipolar disorder (BD) with age. This study specifically aimed to understand differences in the process of cognitive ageing and the factors that might predict who will have more loss of cognitive ability with age. The study recruited over 170 adults aged 25 and older from the greater San Diego area (United States of America), including individuals with clinically-relevant symptoms of mood dysregulation, as indicated by Bipolar I diagnosis, and similarly aged non-BD comparison participants without mental illness. Participants were assessed over two-week periods, repeated annually for three years in the BD group, and at one year in the NC group, from 2016 to 2019.
Study design
Cohort, Cohort - clinical
Number of participants at first data collection
173 (participants)
Age at first data collection
≥ 25 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2016
Primary Institutions
University of California, San Diego (UC San Diego)
Links
reporter.nih.gov/project-details/9517988
doi.org/10.1016/j.psychres.2019.112496
Profile paper DOI
Not available
Funders
Brain and Behavior Research Foundation (BBRF)
National Institute of Mental Health (NIMH)
University of California, San Diego (UC San Diego)
Ongoing?
No
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – online
- Wearable devices
- None
- None
- None
Engagement
Keywords
