Developmental Impact of NICU Exposures (ECHO DINE)
DINE investigates the long-term impact of environmental exposures in neonatal intensive care units (NICUs). The DINE study combines participants from four existing preterm cohorts: the Prematurity and Respiratory Outcomes Program (PROP), the Trial of Late Surfactant (TOLSURF) study, the Preterm Erythropoietin Neuroprotection Trial (PENUT), and the NICU Hospital Exposures and Long-Term Health (NICU-HEALTH) study. DINE participants were recruited between January 2010 and March 2020 and completed annual follow-up visits under the ECHO-Wide Cohort Protocol. The study followed around 800 former preterm infants from the ages of 3 to 10 in eight geographically diverse clinical sites across the United States of America.
Study design
Cohort
Number of participants at first data collection
854 (participants)
Age at first data collection
≤ 12 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2010
Primary Institutions
Albert Einstein College of Medicine
Children's Hospital at Montefiore (CHAM)
Links
reporter.nih.gov/project-details/10914246
classic.clinicaltrials.gov/ct2/show/NCT03061890
nichq.org/wp-content/uploads/2024/09/Echo-Dine-Study-Quick-Facts.pdf
Profile paper DOI
Funders
National Institutes of Health (NIH)
Ongoing?
No
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Physical environment assessment (e.g. pollution, mould)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – unspecified
- None
- Cranial ultrasound
- None
Engagement
Keywords
Consortia and dataset groups
