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Ethanol, Neurodevelopment, Infant and Child Health Survey (ENRICH-1)
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Sample details

ENRICH-1 aimed to explore the effects of moderate alcohol and/or opioid exposure in pregnancy on development. Over 600 pregnant women were recruited from the University of New Mexico (United States of America) prenatal clinics from October 2013 to August 2017. Participants included four study groups: healthy controls who did not use alcohol or opioids during pregnancy, women who used alcohol during pregnancy, patients receiving medications for the treatment of opioid use disorder who did not use alcohol during pregnancy, and opioid use disorder patients who concurrently used alcohol. Baseline data were collected at the prenatal visit, and mothers and their children were followed up at the hospital shortly after delivery. Child development was assessed at 6 months and 20 months of age.

Study design
Cohort - birth, Cohort, Cohort - primary caregiver and child

Number of participants at first data collection

666 (pregnant women)

No information available (children)

Age at first data collection

≥ 18 years (pregnant women)

Birth (children)

Participant year of birth

Varied (pregnant women)

Varied (children)

Participant sex
All

Representative sample at baseline?
No

Sample features

Adults
Alcohol users
Control participants
Mother and child dyad
Pregnant people
Dataset details

Country

United States of America

Year of first data collection

2013

Primary Institutions

University of New Mexico (UNM)

Links

reporter.nih.gov/project-details/9293186

doi.org/10.1111/acer.14545

doi.org/10.1038/pr.2018.26

doi.org/10.1016/j.drugalcdep.2018.02.025

Funders

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

National Institute on Drug Abuse (NIDA)

National Institutes of Health (NIH)

Ongoing?
No

Data types collected

neuroImagingData
mentalHealthData
Quantitative data collection
  • Audio or visual recordings (e.g. of child behaviour, facial expressions)
  • Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
  • Interview – face-to-face
  • Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
Qualitative data collection
  • None
Neuroimaging data collection
  • Electroencephalography (EEG)
  • Magnetoencephalography (MEG)
Linked or secondary data
  • None
Features

Engagement

  • None
  • Keywords

    Alcohol use
    Biological samples/biospecimens
    Fetal development
    Fetal exposure
    Human development
    Neurodevelopment
    Neuroimaging
    Pregnancy
    Pregnancy outcomes
    Prenatal exposures
    Substance use
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