Eurocat NNL is a population-based congenital anomaly registry covering Groningen, Friesland, and Drenthe in the Northern Netherlands from 1981 onwards. All pregnancy outcomes are covered and information is collected on genetic testing, prenatal diagnosis, and risk factors through parental questionnaires (response percentage around 80%), medical records, and pharmacy data. All children and foetuses with a congenital anomaly whose mother was a resident of Groningen, Friesland, or Drenthe at the time of birth are included. Registration is an ongoing process; children can be registered until 10 years after birth and at all gestational ages. Still births, miscarriages, and terminations of pregnancy are also included in the registry.
Study design
Registry, Cohort - open
Number of participants at first data collection
20,500 (participants)
Recruitment is ongoing
Age at first data collection
0 - 12 years (participants)
Participant year of birth
Varied (participants)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
1981
Primary Institutions
University Medical Center Groningen (Universitair Medisch Centrum Groningen, UMCG)
Profile paper DOI
Funders
Dutch Ministry of Health, Welfare, and Sport (VWS)
Ongoing?
Yes
Data types collected
Engagement
Keywords