Fetal Programming of the Newborn and Infant Human Brain
This is a longitudinal, prospective study investigating how prenatal factors can influence fetal programming and early neurodevelopment. From 2011, 147 pregnant women were recruited during the first trimester of pregnancy through prenatal clinics and advertisements at the University of California, Irvine, United States of America. Data were collected from participants at early, mid, and late gestational time points. From this cohort, 86 mothers consented for their infants to undergo MRI scans shortly after birth, with follow-ups conducted at 6 and 12 months post-birth.
Study design
Cohort, Cohort - birth, Cohort - primary caregiver and child
Number of participants at first data collection
147 (mothers)
86 (children)
Age at first data collection
Varied (mothers)
34 - 42 weeks (children)
Participant year of birth
Varied (mothers)
Varied (children)
Participant sex
All
Representative sample at baseline?
No
Sample features
Country
Year of first data collection
2011
Primary Institutions
University of California, Irvine (UCI)
Profile paper DOI
Funders
National Institute of Mental Health (NIMH)
Ongoing?
Yes
Data types collected
- Computer, paper or task testing (e.g. cognitive testing, theory of mind doll task, attention computer tasks)
- Physical or biological assessment (e.g. blood, saliva, gait, grip strength, anthropometry)
- Self-report questionnaire – paper or computer assisted
- None
- Diffusion Tensor Imaging (DTI)
- Functional magnetic resonance imaging (fMRI)
- Magnetic Resonance Imaging (MRI)
- None
Engagement
Keywords
